Changes of Haematobiochemical Parameters during Canine Parvoviral Enteritis

BLERINA DOKU2*; DHIMITER RAPTI1; OLSI DOKU2

1Department of Clinic. Faculty of Veterinary Medicine. Agricultural University of Tirana, Albania

2Veterinary Clinic “Vetmedica”, Tirana. Albania

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Abstract

Canine parvovirus is a highly contagious virus that can affect all dogs, but unvaccinated dogs and puppies younger than four months old are the most at risk. The pathology caused by CPV-2 is very common in Albania despite the existence of an effective vaccine.Changes in haematobiochemical parameters during canine parvoviral enteritiswould be very important for determining the prognosis of the disease. This hypothesis prompted the start of the study. From fecal samples taken from puppies 65 individuals resulted positive. Of all individuals 14 of them (21.5%) failed to survive. All puppies presented leukopenia. In individuals that survived the WBC count began to grow in the first 24-48 hours (p <0.05). In non-survivors the WBC was never higher than 2.1×109 / l at the time of admission in the clinic and in the first 24-48 hours began to decline further (p <0.05). There weren’t significant change in RBC count (p <0.05). In the first   12-24 hours 54% of individuals who did not survive had a PLT count less than 362.28×109 / l compared to only 8% of individuals who survived. Urea and creatinine were higher in survivors compared to non-survivors (p <0.05).These parameters reached normal levels after the start of the treatment in individuals that survived. Urea and creatinine levels in non-survivors continued to decrease until they died. The changes observed in leukocyte, platelet, urea and serum creatinine levels duringfirst stages of canine parvoviral enteritiscan be used to determine prognosis.

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